The thermal performance of high heat flux components in a fusion reactor could be enhanced significantly by the use of nanofluid coolants, suspensions of a liquid with low concentrations of solid nanoparticles. However, before they are considered viable for fusion, the long-term behaviour of nanofluids must be investigated. This paper reports an experiment which is being prepared to provide data on nanofluid stability, settling and erosion in a HyperVapotron device. Procedures are demonstrated for nanofluid synthesis and quality assessment, and the fluid sample analysis methods are described. The end results from this long-running experiment are expected to allow an initial assessment of the suitability of nanofluids as coolants in a fusion reactor.