Molybdenum is a potential material for future nuclear fusion experiments and power plants. It has good thermo-mechanical properties and can be readily fabricated, making it attractive as an alternative material to tungsten (the current leading candidate) for high neutron flux and high thermal load regions of fusion devices. Unfortunately, exposure to those fusion neutrons is predicted to cause significant long-term radioactivity in elemental Mo, which would be a problem during maintenance and decommissioning operations. Simulation predictions indicate that Mo activation could be reduced by isotopic adjustment (biasing). If these predictions are proven, then Mo could be used in future demonstration and commercial reactors without significantly increasing the amount of long-term, higher-level radioactive waste.