A number of tools have recently been developed to study equilibrium and stability in tokamaks with pressure anisotropy. Here we apply these tools to a Mega Ampere Spherical Tokamak (MAST) discharge to calculate equilibrium, Alfven continua and eigenmodes, through to linear growth and nonlinear saturation of a toroidal Alfven eigenmode (TAE); this is the first study of wave growth and saturation for anisotropic equilibria. Comparisons with the standard tools which assume an isotropic pressure reveal various differences in equilibrium and modes: the safety factor profile in the isotropic reconstruction is reversed shear while the anisotropic reconstruction gives normal shear; the isotropic TAE gap is much narrower than the anisotropic gap; and the TAE radial mode structure is wider in the anisotropic case. These lead to a modification in the resonant regions of fast-ion phase space, and produce a 35% larger linear growth rate and an 18% smaller saturation amplitude for the TAE in the anisotropic analysis compared to the isotropic analysis.